🎮IsaacWiki
Runs4 min read

Isaac Items, Shops, and Devil Deals

How to spend keys, when to bomb, and when a deal is actually a wipe.

Treasure vs shop

Early keys usually go to treasure rooms. Shops matter when you need a heart or a bomb to open a secret.

Devil/angel

Angel chance is a playstyle. If you already donated red hearts, commit. Mixed deals often leave you with nothing.

Synergy thinking

Tears, damage, and a way to not die. Homing on 0.9 tears is still slow.

Alt path

Downpour and mirrors wait until you can spare health. They are extra unlocks, not a mandatory tutorial.